In the framework of the Erasmus+ Programme, the LEGO project bridges a growing educational gap in the field of high university education by defining, training and promoting the recognition of an innovative and interdisciplinary professional curriculum, called “Food Microbial Bioinformatician”. The creation of this new profile allows to meet the new research challenges in the field of genomics applied to food safety. Increased accessibility and decrease in the cost of Whole Genome Sequencing (WGS) using Next Generation Sequencing (NGS) have revolutionised clinical and public health microbiology.